Testing and Validation

Test Data Set

Both WGS and WES aligned BAM files were used to test in single and tumor-normal paired modes.

Type Mode Size CPU threads PeakVMemory Run Time
1 WES Single 4GB 72 9.381 GB ~4 min
2 WES Paired 4GB/4GB 72 12.317 GB ~8 min
3 WGS Single 399GB 72 21.042 GB ~2h 40 min
4 WGS Paired 399GB/740GB 72 26.615 GB ~5 hours

Running Tests with NFTest

Ensure NFTest is installed on your system. If it is not installed follow installation instructions in the NFTest documentation.

To test annotators run the command with the annotator of interest:

nftest run [test-paired-01 test-single-normal-01 test-single-tumor-01 test-paired-10 test-single-normal-10 test-single-tumor-10]

Additionally it is possible to modify the nftest.yml file to tune testing. All testing assets can be found in the test/ directory.

For larger jobs a cluster submission tool is available for NFTest.

Validation Tool

Included is a template for validating your input files. For more information on the tool check out: https://github.com/uclahs-cds/tool-validate-nf